CJC-1295N Lyophilized Powder 5mg

Nomenclature & Synonyms

CJC-1295 No DAC is known as Modified Growth Hormone Releasing Factor (GRF) 1-29. It does not have a designated research code other than its common peptide name, and it is derived from the parent compound, Growth Hormone-Releasing Hormone (GHRH).

Structural Characteristics

The amino acid sequence is Tyr-D-Ala-Asp-Ala-Ile-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Ala-Val-Leu-Gly-Gly-Gly-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Met consisting of 30 residues. Notable structural modifications include N-terminal D-alanine substitution to enhance plasma stability.

Molecular Pharmacology

CJC-1295 No DAC targets the Growth Hormone-Releasing Hormone Receptor (GHRHR). It acts as an agonist, primarily activating the cAMP/PKA signaling pathway to stimulate growth hormone release. No distinct EC50 values have been established due to primarily qualitative expression studies.

Research Applications

• Studied for modulation of growth hormone release in pituitary cells.

• Has been shown to improve stability over endogenous GHRH when examined in vitro.

Technical Properties

CJC-1295 No DAC is soluble in sterile water at concentrations up to 2mg/mL. For research use, it is recommended to reconstitute with bacteriostatic water to ensure proper peptide integrity. The lyophilized form is stable at room temperature but should ideally be stored at -20°C; following reconstitution, it should be used within 2 weeks if maintained at 4°C.

Compliance

For laboratory research use only. Not for human or veterinary use. Not intended for diagnostic, therapeutic, or preventive applications.